{"id":705,"date":"2025-01-11T01:52:57","date_gmt":"2025-01-11T00:52:57","guid":{"rendered":"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/?page_id=705"},"modified":"2025-05-27T11:31:51","modified_gmt":"2025-05-27T09:31:51","slug":"quels-sont-les-symptomes","status":"publish","type":"page","link":"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/en\/patients\/what-are-the-symptoms\/","title":{"rendered":"What are the symptoms?"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"705\" class=\"elementor elementor-705\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6a59d85d e-flex e-con-boxed e-con e-parent\" data-id=\"6a59d85d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cfc4de8 elementor-widget elementor-widget-text-editor\" data-id=\"cfc4de8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1>What are the <br \/><strong>symptoms?<\/strong><\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7df8cb63 elementor-absolute elementor-widget elementor-widget-image\" data-id=\"7df8cb63\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2024\/12\/decor-page-title.svg\" class=\"attachment-large size-large wp-image-288\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-428e01a e-flex e-con-boxed e-con e-parent\" data-id=\"428e01a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d6cd66a elementor-widget elementor-widget-shortcode\" data-id=\"d6cd66a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><span><span><a href=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/en\/\"><img decoding=\"async\" alt=\"Home\" src=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/themes\/hello-theme-child-master\/img\/home.svg\" class=\"home-breadcrumb\" \/> Home<\/a><\/span><\/span><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-15d3b5b1 e-flex e-con-boxed e-con e-parent\" data-id=\"15d3b5b1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-591f04bc elementor-widget elementor-widget-text-editor\" data-id=\"591f04bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: left;\" class=\"translation-block\">LES <strong>SYMPT\u00f4MES DE L\u2019IRC<\/strong><\/h2><p style=\"text-align: left;\">Chronic kidney disease often progresses silently in its early stages. The kidneys compensate for the gradual loss of function, delaying the onset of symptoms. This is why the disease can remain asymptomatic for a long time and may only be detected at an advanced stage, when kidney function is already significantly impaired.<sup>22 <\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16c4a146 e-flex e-con-boxed e-con e-parent\" data-id=\"16c4a146\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-63a91004 e-con-full e-flex e-con e-child\" data-id=\"63a91004\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-29257a71 elementor-widget elementor-widget-text-editor\" data-id=\"29257a71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><strong>Physical signs<sup>20,22 <\/sup><\/strong><\/h2><p>The decreased filtering capacity of the kidneys leads to an accumulation of toxins and fluids in the body, causing:<\/p><ul><li><strong>Severe and unexplained fatigue<\/strong> Due to the accumulation of waste in the blood and possible anemia caused by a decrease in erythropoietin production (a hormone produced by the kidneys that stimulates red blood cell production).<\/li><li><strong>Edema:<\/strong> Swelling in the ankles, feet, or face caused by water and salt retention due to impaired kidney function.<\/li><li><strong>Decrease in urine output:<\/strong> Although some patients continue to urinate normally, their ability to eliminate toxins is reduced.<\/li><li><strong>Shortness of breath:<\/strong> Due to anemia or fluid buildup in the lungs (pulmonary edema).<\/li><li><strong>Muscle pain and cramps:<\/strong> Related to an electrolyte imbalance, particularly potassium and calcium, which play a key role in muscle contraction.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6a7d2c7f e-con-full e-flex e-con e-child\" data-id=\"6a7d2c7f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3e4c3d6f elementor-widget elementor-widget-image\" data-id=\"3e4c3d6f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"598\" src=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1-1024x765.jpg\" class=\"attachment-large size-large wp-image-1746\" alt=\"\" srcset=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1-1024x765.jpg 1024w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1-300x224.jpg 300w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1-768x574.jpg 768w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1-16x12.jpg 16w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-1-1.jpg 1327w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-54ba68cf e-flex e-con-boxed e-con e-parent\" data-id=\"54ba68cf\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-104cb29f elementor-widget elementor-widget-text-editor\" data-id=\"104cb29f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"translation-block\"><strong>Digestive<\/strong> and <strong>metabolic disorders<sup>21,22 <\/sup><\/strong><\/h2><p>The accumulation of toxins in the blood (uremia) can cause digestive and metabolic imbalances:<\/p><ul><li><strong>Loss of appetite, nausea, or vomiting:<\/strong> A direct consequence of uremia, which disrupts the functioning of the digestive system.<\/li><li><strong>Metallic taste in the mouth:<\/strong> Due to the accumulation of certain substances, such as urea, which alter taste perception.<\/li><li><strong>Persistent skin itching:<\/strong> Related to the accumulation of toxins under the skin, particularly excess phosphorus.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e445cfa e-flex e-con-boxed e-con e-parent\" data-id=\"e445cfa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-13ad75ac elementor-widget elementor-widget-text-editor\" data-id=\"13ad75ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"translation-block\">Effets sur la <strong>tension et la circulation sanguine<\/strong><strong><sup>3,23<\/sup><\/strong><\/h2><p>The kidneys play a key role in regulating blood pressure and producing red blood cells. Their impairment leads to:<\/p><ul><li><strong>High blood pressure:<\/strong> High blood pressure, which further damages the kidneys, creating a vicious cycle.<\/li><li><strong>Anemia and constant feeling of cold:<\/strong> A decrease in erythropoietin production leads to a reduction in red blood cell count, reducing tissue oxygenation and causing chronic fatigue as well as increased sensitivity to cold.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-30a32820 elementor-widget elementor-widget-image\" data-id=\"30a32820\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"513\" src=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-1024x656.jpg\" class=\"attachment-large size-large wp-image-1747\" alt=\"\" srcset=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-1024x656.jpg 1024w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-300x192.jpg 300w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-768x492.jpg 768w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-1536x984.jpg 1536w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2-18x12.jpg 18w, https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2025\/03\/IMG-patients-3-2.jpg 1588w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-591f1ad elementor-widget elementor-widget-text-editor\" data-id=\"591f1ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: bolder;\">These symptoms should be reported to your doctor promptly to receive the correct diagnosis and prevent disease progression.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Quels sont les sympt\u00f4mes ? LES SYMPT\u00f4MES DE L\u2019IRC L\u2019insuffisance r\u00e9nale chronique \u00e9volue souvent de mani\u00e8re silencieuse aux premiers stades. Les reins compensent la perte progressive de leur fonction, retardant ainsi l\u2019apparition des sympt\u00f4mes. C\u2019est pourquoi la maladie peut rester asymptomatique pendant longtemps et n\u2019\u00eatre d\u00e9tect\u00e9e qu\u2019\u00e0 un stade avanc\u00e9, lorsque la fonction r\u00e9nale est d\u00e9j\u00e0 fortement alt\u00e9r\u00e9e.22 Signes physiques20,22 La diminution de la capacit\u00e9 de filtration des reins entra\u00eene une accumulation de toxines et de liquides dans l\u2019organisme, provoquant : Fatigue intense et inexpliqu\u00e9e : due \u00e0 l\u2019accumulation des d\u00e9chets dans le sang et \u00e0 une possible an\u00e9mie li\u00e9e \u00e0 la baisse de production d\u2019\u00e9rythropo\u00ef\u00e9tine (hormone produite par les reins qui stimule la fabrication des globules rouges). \u0152d\u00e8mes : gonflements au niveau des chevilles, des pieds ou du visage caus\u00e9s par une r\u00e9tention d\u2019eau et de sel due \u00e0 un mauvais fonctionnement des reins. Diminution de la quantit\u00e9 d\u2019urine [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":58,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-705","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.7 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Quels sont les sympt\u00f4mes ? - SANDBOX-TEST-DB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/en\/patients\/comprendre-ma-maladie__trashed\/quels-sont-les-symptomes\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Quels sont les sympt\u00f4mes ?\" \/>\n<meta property=\"og:description\" content=\"Quels sont les sympt\u00f4mes ? LES SYMPT\u00f4MES DE L\u2019IRC L\u2019insuffisance r\u00e9nale chronique \u00e9volue souvent de mani\u00e8re silencieuse aux premiers stades. Les reins compensent la perte progressive de leur fonction, retardant ainsi l\u2019apparition des sympt\u00f4mes. C\u2019est pourquoi la maladie peut rester asymptomatique pendant longtemps et n\u2019\u00eatre d\u00e9tect\u00e9e qu\u2019\u00e0 un stade avanc\u00e9, lorsque la fonction r\u00e9nale est d\u00e9j\u00e0 fortement alt\u00e9r\u00e9e.22 Signes physiques20,22 La diminution de la capacit\u00e9 de filtration des reins entra\u00eene une accumulation de toxines et de liquides dans l\u2019organisme, provoquant : Fatigue intense et inexpliqu\u00e9e : due \u00e0 l\u2019accumulation des d\u00e9chets dans le sang et \u00e0 une possible an\u00e9mie li\u00e9e \u00e0 la baisse de production d\u2019\u00e9rythropo\u00ef\u00e9tine (hormone produite par les reins qui stimule la fabrication des globules rouges). \u0152d\u00e8mes : gonflements au niveau des chevilles, des pieds ou du visage caus\u00e9s par une r\u00e9tention d\u2019eau et de sel due \u00e0 un mauvais fonctionnement des reins. Diminution de la quantit\u00e9 d\u2019urine [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/en\/patients\/comprendre-ma-maladie__trashed\/quels-sont-les-symptomes\/\" \/>\n<meta property=\"og:site_name\" content=\"SANDBOX-TEST-DB\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Physidia\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-27T09:31:51+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/physidia-sandbox-gnfngfcwfuenfwbd.francecentral-01.azurewebsites.net\/wp-content\/uploads\/2024\/12\/decor-page-title.svg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" 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